Neoproteoglycans in tissue engineering

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Neoproteoglycans in tissue engineering.

Proteoglycans, comprised of a core protein to which glycosaminoglycan chains are covalently linked, are an important structural and functional family of macromolecules found in the extracellular matrix. Advances in our understanding of biological interactions have lead to a greater appreciation for the need to design tissue engineering scaffolds that incorporate mimetics of key extracellular ma...

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BACKGROUND Restoration of craniofacial bone defects has been a concern for oral and maxillofacial surgeons. In this study, the healing effect of fibrin glue scaffold was compared with autologous bone graft in mandibular defects of rabbit. METHODS Bilateral unicortical osteotomy was performed in the diastema region of 10 male Dutch rabbits. The subjects were randomly divided into 2 equal group...

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tissue engineering in dentistery

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ژورنال

عنوان ژورنال: FEBS Journal

سال: 2013

ISSN: 1742-464X

DOI: 10.1111/febs.12187